Serotonin levels might play an important role in how eating disorders develop and how they can best be treated. MelindaKarth explains.
Unfortunately, we know very little about serotonin's role in avoidant restrictive food intake disorder and pica.
Nonetheless, pharmacology studies have shown that serotonin medications reduce ARFID and pica symptoms, possibly by decreasing anxiety about meals and food, as well as compulsiveness.The Challenges of Making Conclusions About Serotonin and Eating DisordersDespite the promise of these findings, it is too soon to make definitive conclusions about serotonin's role in EDs.
One reason for this is that we lack the technology to analyze specific molecular functions in people with EDs. Animal models of EDs can clarify some of these mysteries, but only to a certain extent. We need more precise technologies to fully understand the molecular aspects of EDs. Additionally, because most research studies observe serotonin in people currently ill with or recovered from an ED, it is difficult to determine what serotonin levels were likedevelopmentthe ED change the person's serotonin levels? Malnutrition and other side effects of an ED can also make studying serotonin difficult.
This shouldn't be discouraging, though. While we're still struggling to find the best ways to study serotonin in EDs, the limited evidence we do have has demonstrated that serotonin is likely one of the most important chemicals involved in ED development and its persistence. This alone can help guide future pharmacological treatments for EDs, making the future of ED treatment bright.2)Jonnakuty, C., & Gragnoli, C. .
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