The 'Great Escape' by SARS-CoV-2 XBB.1 SARSCoV2 Coronavirus Disease COVID XBB1 BM111 BQ11 Omicron LancetMicrobe ErasmusMC Cambridge_Uni
By Neha MathurJan 17 2023Reviewed by Danielle Ellis, B.Sc. This exercise could prove fruitful in identifying SARS-CoV-2 strains for the next-generation coronavirus disease 2019 vaccines.
Background It is highly concerning that novel Omicron subvariants are emerging at an extraordinary rate, despite vaccination and prior infection-induced immunity in the majority of the global population. They used a SARS-CoV-2 hamster model for their experiments. First, they infected test animals with Omicron BA.5 subvariant, genetically close to Omicron BA.2, but varying by two deletions and three substitutions in the spike amino acid sequence. Next, they assessed neutralizing antibody titers for all serum samples and variants, including Omicron BA.5, BM.1.1.1, BQ.1.1, and XBB.1.
Further, the study data revealed that Omicron BA.5 antiserum samples neutralized BA.2 and BQ.1.1 substantially but not Omicron BM.1.1.1. Strikingly, none of the serum samples effectively neutralized Omicron XBB.1. In both two-dimensional and three-dimensional maps, Omicron XBB.1, BM.1.1.1, and BQ.1.1 were the farthest from all preceding variants, with no marked improvement with the higher number of dimensions.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Overall patterns of SARS-CoV-2 caused by variants of concern among children and adolescentsOverall patterns of SARS-CoV-2 caused by variants of concern among children and adolescents medrxivpreprint UniBasel_en unibern institutpasteur sheffielduni SARSCoV2 covid coronavirus covid variantsofconcern childhealth teenagers
続きを読む »
Haemorrhage of human foetal cortex associated with SARS-CoV-2 infectionMassimo et al. report the presence of SARS-CoV-2 in first and second trimester foetal brain tissue in association with cortical haemorrhages. The haemorrhages w
続きを読む »
Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamstersIntranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters biorxivpreprint moderna_tx mRNA LipidNanoparticle NanoparticleVaccine SARSCoV2 COVID19 Vaccine HamsterModel
続きを読む »
Study investigates the spectrum of antibody immunity across several SARS-CoV-2 variantsStudy investigates the spectrum of antibody immunity across several SARS-CoV-2 variants medrxivpreprint UniofExeter antibody immunity protein spike SARSCoV2 covid coronavirus COVID19
続きを読む »
Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new researchArtemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research researchsquare UCSanDiego ArtemisiaArgyi SARSCoV2 COVID19 Coronavirus Phytochemicals
続きを読む »
S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein AS. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A WesternU SARSCoV2 bacteria virus covid coronavirus covid
続きを読む »