Artemisia argyi plant extracts and phytochemicals shown to inhibit SARS-CoV-2 in new research researchsquare UCSanDiego ArtemisiaArgyi SARSCoV2 COVID19 Coronavirus Phytochemicals
By Tarun Sai LomteJan 16 2023Reviewed by Aimee Molineux In a recent study posted to Research Square*, researchers reported that Artemisia argyi extracts and phytochemicals could inhibit severe acute respiratory syndrome coronavirus 2 .
The study and findings The present study evaluated the potential activity of A. argyi extracts and known phytochemicals against SARS-CoV-2. Fluorescence resonance energy transfer -based enzymatic assays were performed to study the effects of 14 known A. argyi compounds on cellular enzymes involved in viral spike processing.
Drug Discovery eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Having established that the phytochemicals target proteins involved in cell entry of SARS-CoV-2, the researchers next examined the cytotoxicity of A. argyi extracts, umbelliferone, and eriodictyol in the BEAS-2B cell line. The 50% cytotoxicity concentrations of A. argyi extracts, umbelliferone, and eriodictyol were 4471 μg/ml, 302.4 μM, and 212.6 μM, respectively.
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