Sleep could hold surprising anxiety-reducing benefits after a stressful situation

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Sleep could hold surprising anxiety-reducing benefits after a stressful situation
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Studies in mice raise questions about how our brains work.

The researchers behind this experiment weren't interested in chronic stress that goes on for days or longer. Joëls and de Kloet say the difference lies in how long the stress lasts. The short, happens-then-it's-done stressor of losing a fight with another mouse"may have different consequences than the wear and tear caused by a chronic state of stress," they write. Chronic, unpredictable stress is what a lot of people feel in their day-to-day lives.

"pathway is key to restorative sleep after social defeat, preventing a lasting state of anxiety," Joëls and de Kloet write. Interestingly, the brain cells in the VTA are GABA neurons, not the better-known dopamine neurons that are involved in everything from rewards and learning to social competence and stress.This pathway caused a couple of different effects. It was enough to send the losers to sleep , and it helped them cope with the psychological impact of the loss.

As scientists answer these questions, they'll be able to put the knowledge to use. As Joëls and de Kloet write,"[k]nowing the essential steps in the brain may help steer future interventions in rodents and perhaps even humans after stressful experiences, be it through cognitive therapy or pharmacotherapy or maybe, one day, genetic interference.

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