Logic-gated antibody pairs that selectively act on cells co-expressing two antigens
Animal experiments were performed in compliance with the Dutch animal protection law translated from the directives and if applicable, the Code of Practice ‘animal experiments for cancer research’ and were approved by the Dutch Central Committee for animal experiments and by the local ethical committee.
Human pluripotent stem cell -humanized NSG mice were purchased from Jackson from three HPSC donors. Humanization levels were confirmed on arrival by flow cytometry , and randomization was performed based on human CD45 counts and the donors. One day before the study all animals were injected intraperitoneally with 8 mg IVIg . NSG-HIS mice were treated intravenously with antibody mixtures at a combined dose of 0.5 mg kg) and red blood cell Lysis buffer .
All fluorescently labeled antibodies specific for the cell markers used to define cell populations are listed in Supplementary Table
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice - Nature BiotechnologyCancers with common KRAS mutations can be treated with an inhibitor of lysosomal acidification in mice.
続きを読む »
9 nature-inspired decorating tips to make your home a more relaxing spaceThere are several easy and right-before-your-nose tweaks you can do to make your home a more hospitable space for your mental health.
続きを読む »
Youth Environmental Program Helps Teens Explore Nature, Recognize Sociological Impacts of Climate ChangeAs brutal heat waves sweep across the globe, calls to address the effects of climate change have become increasingly urgent. But in addition to large-scale policy efforts, making lasting change often starts with individuals.
続きを読む »
Alignment of fractures on Bennu’s boulders indicative of rapid asteroid surface evolution - Nature GeoscienceFractures on the asteroid Bennu imaged by the OSIRIS-REx spacecraft are consistent with cracking induced by diurnal temperature variations over geologically rapid timescales.
続きを読む »