‘Chameleon cancers’ avoid treatment by changing colors and identity

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‘Chameleon cancers’ avoid treatment by changing colors and identity
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The blood cancer is difficult to treat because it modifies itself to evade therapy. Find out more at 🚀

The researchers from the University of Birmingham and Newcastle University in the U.K., and the Princess Máxima Center in The Netherlands, examined the responses of children undergoing therapy for blood cancer treatment.There have been huge improvements and discoveries in treating blood cancers over the last 50 years, with 90% of children being cured from the blood cancer acute lymphoblastic leukemia .

Some leukemias can evade immunotherapies by stopping the production of cell proteins that the therapy targets. The team examined tumorous DNA of twelve children and adults with ALL, whose cancer showed the change in the MLL gene. They noticed that on-off switches were changed.

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