A growing number of scientists is trying to help people reach a goal humans have been chasing throughout history: staying active and vital in old age
This microscope photo provided by the Mayo Clinic in August 2022 shows senescent myoblast cells. Senescent cells resist apoptosis, or programmed cell death, and characteristically get big and flat, with enlarged nuclei. They release a blend of molecules, some of which can trigger inflammation and harm other cells — and paradoxically also stimulate the growth of malignant cells and fuel cancer, says Mayo Clinic researcher Nathan LeBrasseur.
With the number of people 65 or older expected to double globally by 2050, cellular senescence is"a very hot topic," says Viviana Perez Montes of the National Institutes of Health. According to an Associated Press analysis of an, there have been around 11,500 total projects involving cellular senescence since 1985, far more in recent years.
“I’m not looking for the fountain of youth,” Wiley says. “I’m looking for the fountain of not being sick when I’m older.”Leonard Hayflick, the scientist who discovered cellular senescence in 1960, is himself vital at 94. He's a professor of anatomy at the University of California, San Francisco, and continues to write, present and speak on the topic.
The finding, Hayflick says, challenged"60-year-old dogma" that normal human cells could replicate forever. A paper he authored with colleague Paul Moorhead was rejected by a prominent scientific journal, and Hayflick faced a decade of ridicule after it was“It followed the usual pattern of major discoveries in science, where the discoverer is first ridiculed and then somebody says, ‘Well, maybe it works’ … then it becomes accepted to some extent, then becomes more widely accepted.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Human ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types - Nature BiotechnologyHuman ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types
続きを読む »
Families play audio of Uvalde shooting victims’ voices outside Abbott’s home during rally for gun reformThe relatives spent Saturday urging Gov. Greg Abbott to call a special session to raise the minimum age to purchase an automatic rifle from 18 to 21 years old.
続きを読む »
'Funny Pages': A Portrait of the Comic-Book Artist as a Gross and Clueless Young ManOwen Kline's 'Funny Pages,' about an aspiring cartoonist desperate to ditch his suburban upbringing, reminds us that people are weird and gross and awkward — and that's really fun to watch. K. Austin Collins' review
続きを読む »
A 22-year-old went missing in California 3 weeks ago. Police are now treating it as a criminal matterPolice in central California say they are treating the early August disappearance of 22-year-old Jolissa Fuentes, last seen leaving a convenience store, as a criminal matter.
続きを読む »
What Old Dogs Can Teach Us About AgingScientists are studying different dog breeds to gain new insights into the aging process — both for them, and for us.
続きを読む »
We Ride In Toyota’s Hydrogen-Powered Big RigHydrogen fuel cell trucks could be the quiet revolution
続きを読む »