Lawrence Faucette has become the second patient in the world to receive a successful transplant of a genetically modified pig heart.
“We are once again offering a dying patient a shot at a longer life, and we are incredibly grateful to Mr. Faucette for his bravery and willingness to help advance our knowledge of this field,” said Bartley P. Griffith, MD, who surgically transplanted the pig heart into both the first and second patient at UMMC. “We are hopeful that he will get home soon to enjoy more time with his wife and the rest of his loving family.
His wife, Ann Faucette, added, “We have no expectations other than hoping for more time together. That could be as simple as sitting on the front porch and having coffee together." The US Food and Drug Administration granted emergency approval for the surgery on compassionate grounds, as it had done for Bennett in 2022. This approval process is used when an experimental medical product, in this case, the genetically modified pig’s heart, is the only option available for a patient faced with a serious or life-threatening medical condition, said the press release.Virginia-based company Revivicor provided the genetically modified pig for Faucette’s xenotransplantation.
“We are continuing to pursue the pathway to clinical trials by providing important new data on pre-clinical research that has been requested by the FDA,” said Dr. Muhammad M Mohiuddin, professor of surgery at UMSOM. “The FDA used our data from these new studies, as well as our experience with the first patient, to determine that we were ready to attempt a second transplant in an end-stage heart disease patient who had no other treatment options.
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