ICYMI: In the past few months several new strains of COVID19 have taken hold in the US, transforming into the country's top coronavirus culprits. This is what you should know about several of these new subvariants, including BQ.1, BQ.1.1 and XBB.1.5.
After noticing that Omicron strains seem to share similar spike protein mutations and similar mild symptoms, Boston University scientists decided to develop their own unique variant of the virus. This strain combined the spike protein mutations typical of Omicron variants with other traits typical of older, non-Omicron variants of SARS-CoV-2, all in an attempt to determine whether the structure of the spike protein is what determines the severity of the disease after an infection does occur.
The scientists tested their strain on mice. While their artificial varietal killed a shocking 80 percent of the mice on which it was tested, the older, non-Omicron variants of SARS-CoV-2 without altered spike proteins were much more deadly, killing 100 percent of the test organisms. The mortality rate of the scientists' strain was relatively similar to the original SARS-CoV-2 variants without altered spike proteins. Therefore, the researchers concluded that the spike protein mutations do not determine the seriousness of COVID-19 symptoms whenever the disease does develop.
Ultimately, while they couldn't pinpoint what determines symptom severity, the silver lining is that the Boston University variant isn't in the mix of increasingly widespread strains like BQ.1, BQ.1.1 and XBB.1.5.
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