What factors impacted the adoption of self-management behavior of patients with chronic kidney disease during COVID-19? Gazi_Universite AnkaraUni kidney kidneydisease disease COVID19 coronavirus covid
By Bhavana KunkalikarMar 2 2023Reviewed by Danielle Ellis, B.Sc. *Important notice: Research Square publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information.
During the pandemic, it was observed that social isolation, healthcare disruptions, and lockdowns impacted therapy and management, with a lack of follow-up potentially leading to patient adversity. Hence, the importance of CKD patient self-management increased during the COVID-19 pandemic. From July to December 2021, semi-structured face-to-face interviews were used to collect data using a qualitative approach. Three authors devised the interview guide after evaluating pertinent literature and investigating the effects of prior pandemics on the disease management behavior of chronic patients. The framework analysis was implemented in six steps: transcription, familiarization, coding, framework application, data charting, and data interpretation.
Patients with negative memories, such as kidney transplant rejection, were more likely to perceive COVID-19 as severe. Furthermore, the loss of loved ones or friends because of COVID-19 affected the perception of COVID-19 severity. Some patients disclosed that they had to postpone or cancel their routine hospital visits out of concern about contracting COVID-19. This resulted in a disturbance in their treatment, and they thought they were unsuccessful in self-managing the treatments.
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Efficacy of first dose of covid-19 vaccine versus no vaccination on symptoms of patients with long covid: target trial emulation based on ComPaRe e-cohortObjective To evaluate the effect of covid-19 vaccination on the severity of symptoms in patients with long covid. Design Target trial emulation based on ComPaRe e-cohort. Data source ComPaRe long covid cohort, a nationwide e-cohort (ie, a cohort where recruitment and follow-up are performed online) of patients with long covid, in France. Methods Adult patients (aged ≥18 years) enrolled in the ComPaRe cohort before 1 May 2021 were included in the study if they reported a confirmed or suspected SARS-CoV-2 infection, symptoms persistent for |3 weeks after onset, and at least one symptom attributable to long covid at baseline. Patients who received a first covid-19 vaccine injection were matched with an unvaccinated control group in a 1:1 ratio according to their propensity scores. Number of long covid symptoms, rate of complete remission of long covid, and proportion of patients reporting an unacceptable symptom state at 120 days were recorded. Results 910 patients were included in the analyses (455 in the vaccinated group and 455 in the control group). By 120 days, vaccination had reduced the number of long covid symptoms (mean 13.0 (standard deviation 9.4) in the vaccinated group v 14.8 (9.8) in the control group; mean difference −1.8, 95% confidence interval −3.0 to −0.5) and doubled the rate of patients in remission (16.6% v 7.5%, hazard ratio 1.93, 95% confidence interval 1.18 to 3.14). Vaccination reduced the effect of long covid on patients' lives (mean score on the impact tool 24.3 (standard deviation 16.7) v 27.6 (16.7); mean difference −3.3, 95% confidence interval −5.7 to −1.0) and the proportion of patients with an unacceptable symptom state (38.9% v 46.4%, risk difference −7.4%, 95% confidence interval −14.5% to −0.3%). In the vaccinated group, two (0.4%) patients reported serious adverse events requiring admission to hospital. Conclusion In this study, covid-19 vaccination reduced the severity of symptoms and the effect of long covid on patients' social,
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