Vaccines could be the 'next big thing' in cancer treatment, scientists say

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Vaccines could be the 'next big thing' in cancer treatment, scientists say
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The next big advance in cancer treatment could be a vaccine.

"We're getting something to work. Now we need to get it to work better," said Dr. James Gulley, who helps lead a center at the National Cancer Institute that develops immune therapies, including cancer treatment vaccines.

"Even if that chance is a little bit, I felt like it's worth it," said Jade, who is also getting standard treatment. In Philadelphia, Dr. Susan Domchek, director of the Basser Center at Penn Medicine, is recruiting 28 healthy people with BRCA mutations for a vaccine test. Those mutations increase the risk of breast and ovarian cancer. The idea is to kill very early abnormal cells, before they cause problems. She likens it to periodically weeding a garden or erasing a whiteboard.

People with the inherited condition Lynch syndrome have a 60% to 80% lifetime risk of developing cancer. Recruiting them for cancer vaccine trials has been remarkably easy, said Dr. Eduardo Vilar-Sanchez of MD Anderson Cancer Center in Houston, who is leading two government-funded studies on vaccines for Lynch-related cancers.Drugmakers Moderna and Merck are jointly developing a, with a large study to begin this year.

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