In the latest in the quest to save human lives with organs from genetically modified pigs, surgeons in Alabama transplanted a pig’s kidneys into a brain-dead man.
- Researchers on Thursday reported the latest in a surprising string of experiments in the quest to save human lives with organs from genetically modified pigs.
Similar experiments have made headlines in recent months as research into animal-to-human transplants heats up. For a little over three days, until the man’s body was removed from life support, the pair of pig kidneys survived with no sign of immediate rejection, her team reported Thursday in the American Journal of Transplantation.
The research was conducted in September after Jim Parsons, a 57-year-old Alabama man, was declared brain-dead from a dirt bike racing accident. Animal-to-human transplants, what’s called xenotransplantation, have been attempted without success for decades. People’s immune systems almost instantly attack the foreign tissue. But scientists now have new techniques to edit pig genes so their organs are more human-like — and some are anxious to try again.
Hurdles remain before formal testing in people begins, including deciding who would qualify to test a pig organ, said Karen Maschke, a research scholar at the Hastings Center who will help develop ethics and policy recommendations for the first clinical trials under a grant from the National Institutes of Health.
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