We're thrilled to introduce the winners of the 2023 Canada GairdnerAwards. Find out how these eight scientists are changing the world with groundbreaking biomedical and global health research.
recognize international excellence in fundamental research impacting human health. This year’s eight laureates, announced on March 30, have helped to advance our understanding of some of the world’s most pressing biomedical and global health issues. Through their relentless pursuit of scientific knowledge and commitment to excellence, these laureates have improved the lives of countless individuals around the world.
This is just one of the many areas in which Belizán has impacted maternal health for the better. Belizán was also the first to document, as well as design, test, and implement landmark interventions addressing the issue of unnecessary increased use of cesarean sections. His research has also led to a decrease in unnecessary routine episiotomy worldwide, including in Canada and the US.
In 2020, the organizers of the biennial Critical Assessment of Protein Structure Prediction officially recognized AlphaFold2 as a solution to the 50-year grand challenge of protein structure prediction. AlphaFold2 has been used to produce structure predictions for more than 200 million proteins—nearly every protein known to science—which DeepMind has made freely available via the AlphaFold Protein Structure Database.
He recruited Jumper, who had developed machine learning methods to simulate protein dynamics while receiving his PhD in Chemistry from the University of Chicago, in 2017. Jumper became the project’s research lead in 2018, redesigning the system’s architecture into what would become AlphaFold2. Both say they’re honored and delighted to receive recognition from Gairdner and see it as a win for the entire team at DeepMind.
Christopher Mushquash, Ph.D., C.Psych., Professor, Department of Psychology, Lakehead University; Psychologist, Dilico Anishinabek Family Care; Vice President Research, Thunder Bay Regional Health Sciences Centre; Chief Scientist, Thunder Bay Regional Health Research Institute “This recognition is a tremendous honor,” Mushquash says. “However, more important to me is that this award—and the opportunities that the Gairdner Foundation provides laureates to engage with a broad range of audiences—will ensure that there is the opportunity for additional dialogue on Indigenous community-based research in mental health and addiction.”
Today, Zadeh’s research focuses on advancing our understanding of brain tumors through genomic analysis. Her work on meningiomas—the most common type of brain tumors, which have limited treatment options—has identified four molecular groups that can reveal insights into tumor behavior. “If you look at the field of neuro-oncology, ultimately, we have not had a successful clinical trial in the last two decades that has made a major impact on a person’s outcome,” she says. “I think that paradigm shift has to come from designing clinical trials based on data and molecular information about the biology of the tumor. We need some outside-of-the-box thinking to develop more nimble strategies.
E Peter Greenberg, PhD, Eugene and Martha Nester Endowed Professor of Microbiology, Department of Microbiology and Molecular & Cellular Biology Program, University of Washington School of Medicine Greenberg, who had studied under Hastings and, in 1978, founded his own lab to explore cell communication, says Silverman’s findings provided just what his team had been looking for. “We were off to the races,” he says. He worked to further characterize the genes involved and served as senior author on a 1994 paper that coined the term quorum sensing. He not only showed that this communication existed in other types of bacteria, but he also discovered nearly all major steps in its mechanism.
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