There is a worrying amount of fraud in medical research

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There is a worrying amount of fraud in medical research
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Most are unlikely to sway clinical practice. But some fraudsters have been the inspiration for specific medical interventions which have turned out to be useless, or even harmful

“From that moment I was alert,” says Dr Mol. And his alertness was not merely as a reader of published papers. He was also, at the time, an editor of the, and frequently also a peer reviewer for papers submitted to other journals. Sure enough, two papers containing apparently fabricated data soon landed on his desk. He rejected them. But, a year later, he came across them again, except with the fishy data changed, published in another journal.

Yet journals can take years to retract, if they ever do so. Going by these numbers, roughly one in 1,000 papers gets retracted. That does not sound too bad. However, Ivan Oransky, one of Retraction Watch’s founders, reckons, based on various studies of the matter and reports from sleuths, that something more like one in 50 papers has results which are unreliable because of fabrication, plagiarism or serious errors.

It is a particular problem in China. Unrealistic publication quotas are often needed to obtain the best jobs in hospitals, and those who publish in top journals also get big cash bonuses. Not surprisingly, China is thus a country that has developed a thriving paper-mill industry. Indeed, almost all retractions linked to paper mills list Chinese authors.

Many fake papers are me-too studies, supporting treatments already backed by other work. For the most part, these are unlikely to sway clinical practice. But some fraudsters have been the inspiration for specific medical interventions which have turned out to be useless, or even harmful.

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