France has banned doctors from prescribing hydroxychloroquine to COVID-19 patients over fears about its safety, after the World Health Organization expressed similar concerns.
Evans said an accurate summary of the situation would be to say that"weak results [were] blown out of proportion."allowed it to be used off-label, while proper clinical trials were set up, Preston explained., many believing the drug to be safe to use in humans due to the long history of use. Thus, it was a case of 'might do some good, won't do any harm,'" he said.
"We are very sure that it will, rarely, cause abnormalities in heart rhythm, and to do this in otherwise healthy people makes the balance of benefit and harm lean towards harm unless there is very convincing evidence it preventsHe added:"I wouldn't take it for precaution unless WHO proves otherwise."the promotion ofis an example"of people allowing the emotion of the moment get in the way of the evidence.
"There was some weak evidence to suggest it could be useful, and hence formally assessing its utility was entirely reasonable. However, recommending its use outside of clinical trials until we knew whether or not the drug worked was, I think, a mistake." The situation demonstrates that controlled trials must be carried out before a drug can be declared as effective, said Preston,"and to be fair most scientists and medics have said this throughout."
He added:"The involvement of some high profile personalities complicated the situation greatly—but in the end, the data will speak loudest."
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