'The main event': Moderna begins final phase of COVID-19 vaccine study

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'The main event': Moderna begins final phase of COVID-19 vaccine study
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'This research study is something that I can do personally to benefit ... humanity,' said one volunteer. Thousands more are needed.

A preliminary assessment of how Moderna's phase 3 trial is progressing is expected after researchers record the first 50 cases of COVID-19 among the participants. That could be sometime this fall or winter.

What these trials won't be able to answer, however, is how long immunity might last."It's one of the great unknowns," Hoge said. Moderna's vaccine is likely to require two doses, but it's possible a third will be necessary. Essink said his team is"looking for higher-risk patients, for more severe disease." That includes people of different ages and races, as well as those with comorbidities, such as heart disease, Type 2 diabetes and other risk factors.

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