Food allergies, triggered by specific allergens, can lead to severe reactions like anaphylaxis. However, innovative treatments such as immunotherapy are revolutionizing allergy management.
Emerging technologies in allergy detectionChallenges and considerations Accurate testing is crucial in identifying food sensitivities, enabling tailored treatment plans for individuals to safely navigate their dietary needs and improve their quality of life.
However, food allergy treatment has undergone significant transformation in the past decades. Initial strategies were limited to avoidance and emergency management, but advancements saw the introduction of oral, sublingual, and epicutaneous immunotherapies. Now, cutting-edge biotechs are propelling personalized medicine, paving the way for groundbreaking treatments using gene therapy and monoclonal antibodies.
AI has been utilized to predict the development and persistence of food allergies in pediatric patients. A Deep Learning framework, employing long short-term memory, was proposed to forecast milk, egg, and peanut allergies in infants from birth to 3 years old using gut microbiome and food allergen-specific serum IgE profiles from the DIABIMMUNE dataset. The DL tool's performance showed promise in predicting clinical food allergy status.
Related StoriesAdditionally, Omalizumab , an off-label monoclonal antibody, is enhancing oral immunotherapy by reducing anaphylaxis risks, with ongoing research into its potential to improve OIT's safety and efficacy.¹¹,¹² Meanwhile, Palforzia, the first FDA-approved immunotherapy for peanut allergies, aims to lessen allergic reactions from accidental peanut exposure.
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