The Devils Hole pupfish is so inbred that it shouldn’t be alive

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The Devils Hole pupfish is so inbred that it shouldn’t be alive
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New research reveals exactly how inbred the Devils Hole pupfish is.

The Devils Hole pupfish is small, blue and incredibly endangered. It also may be the most inbred creature on Earth.

That isolation has led to some very dramatic genetic consequences, scientists reported Nov. 2 in the journal Proceedings of the Royal Society B . They found that Devils Hole pupfish genomes are 58% identical, on average —"the equivalent of five to six generations of full sibling matings," said Christopher Martin , an evolutionary biologist at the University of California, Berkeley and senior author of the new study.

"The genome is a complex place," Martin said. He and his team plan to study the fishes' genetics in greater detail to determine what, exactly, each of their genes is doing and how they're compensating for genomic losses.

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