Genetic characteristics that influence the risk of Parkinson's disease (PD) due to pesticide exposure.
By Pooja Toshniwal PahariaMay 1 2024Reviewed by Lily Ramsey, LLM In a recent study published in npj Parkinson's Disease, researchers examined genetic characteristics that influence the risk of Parkinson's disease due to pesticide exposure.
About the study In the present study, researchers investigated the genetic contributions to PD risk in the presence of chronic pesticide exposure. They compared variation frequencies to most racially comparable White European and non-Hispanic populations in the gnomAD database and racially equivalent Hispanic groups.
They used the third version of the Movement Disorder Society-Unified PD Rating Scale to assess PD progression. Instead, the bulk of variations represented the third and fourth group genes, which are distinguished by inter-protein communications with PD-related genes or elevated expressions in substantia nigral cells, respectively.
Pesticide Autophagy Chronic Gene Genes Parkinson's Disease Pathophysiology Protein Research
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