As brain tumour diagnoses are up by 30%, here are seven symptoms we should all be aware of
The number of people diagnosed with brain tumours has risen by 30% in the last 20 years, new figures suggest.
According to the NHS, a brain tumour occurs due to the growth of cells in the brain that multiplies in an abnormal, uncontrollable way. The severity of brain tumours vary, depending on how big they grow and how likely they are to return after treatment. The charity claims progress for brain tumours has continued to lag behind survival improvements seen in other diseases.
Dr Catherine McBain, a consultant clinical oncologist at The Christie in Manchester, has outlined seven possible signs which may be linked to brain tumour. 3. Marked speech disturbance Slurred speech, being unable to find your words or coming out with the wrong words. Struggling to find a word sometimes is normal; but it would become worrying if it was becoming steadily worse over a period of weeks or months, and was associated with other symptoms.
6. Difficulty reading or interpreting words You may notice that over a few weeks, you’re increasingly struggling to write emails or send texts, or to work out what subtitles or words in a book say – you may be able to see the words clearly, but the brain refuses to interpret them or make sense of them.
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Acute kidney injury in critical COVID-19: a multicenter cohort analysis in seven large hospitals in Belgium - Critical CareBackground Acute kidney injury (AKI) has been reported as a frequent complication of critical COVID-19. We aimed to evaluate the occurrence of AKI and use of kidney replacement therapy (KRT) in critical COVID-19, to assess patient and kidney outcomes and risk factors for AKI and differences in outcome when the diagnosis of AKI is based on urine output (UO) or on serum creatinine (sCr). Methods Multicenter, retrospective cohort analysis of patients with critical COVID-19 in seven large hospitals in Belgium. AKI was defined according to KDIGO within 21 days after ICU admission. Multivariable logistic regression analysis was used to explore the risk factors for developing AKI and to assess the association between AKI and ICU mortality. Results Of 1286 patients, 85.1% had AKI, and KRT was used in 9.8%. Older age, obesity, a higher APACHE II score and use of mechanical ventilation at day 1 of ICU stay were associated with an increased risk for AKI. After multivariable adjustment, all AKI stages were associated with ICU mortality. AKI was based on sCr in 40.1% and UO in 81.5% of patients. All AKI stages based on sCr and AKI stage 3 based on UO were associated with ICU mortality. Persistent AKI was present in 88.6% and acute kidney disease (AKD) in 87.6%. Rapid reversal of AKI yielded a better prognosis compared to persistent AKI and AKD. Kidney recovery was observed in 47.4% of surviving AKI patients. Conclusions Over 80% of critically ill COVID-19 patients had AKI. This was driven by the high occurrence rate of AKI defined by UO criteria. All AKI stages were associated with mortality (NCT04997915).
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