Exclusive: A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimers disease recently died from a massive brain hemorrhage that some researchers link to the drug.
A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimer’s disease recently died from a massive brain hemorrhage that some researchers link to the drug. The clinical trial death, described in an unpublished case reporthas obtained, is the second thought to be associated with the antibody called lecanemab.
Castellani, his co-authors, and other researchers say the newly disclosed death suggests that tPA and perhaps other, less potent blood thinners pose safety considerations for Alzheimer’s patients receiving the antiamyloid antibody drugs, including lecanemab.
If approved, lecanemab would be the second antiamyloid drug to reach the clinic. Aducanumab, a recently approved drug for Alzheimer’s disease also from Eisai and Biogen, is now on the market as Aduhelm. But many Alzheimer’s researchers question the evidence that aducanumab works and wereNow some urge caution about its potential successor.
During the 18-month core trial, the woman might have received either the antibody or the placebo. But there was no question that she was given the antibody during the month preceding her death as part of an open-label trial extension, in which participants who want to take the experimental medication can do so.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Kylian Mbappé Scores in Second Straight Game at World CupThe French phenom scored in his second consecutive game to open the 2022 World Cup, this time giving his team a 1-0 lead against Denmark on Saturday. Here's a recap.
続きを読む »
The Second Coming of Lynette Yiadom-BoakyeIt’s the second coming of British artist Lynette Yiadom-Boakye at the Tate Britain. Her 2020 show “Lynette Yiadom-Boakye: Fly in League With the Night” was disrupted by COVID-19 when it debuted in December 2020 as the museum shut its doors.
続きを読む »
Laval celebrates as Huskies come up short in second consecutive Vanier CupThe U of S Huskies lost 30\u002D24 to Laval in Saturday\u0027s Vanier Cup — their second national\u002Dtitle loss in as many years.
続きを読む »
Walker enjoying second act in HollywoodLonnie Walker once thought he would be a Spur for life. Instead, the 23-year-old guard has...
続きを読む »
Trinity falls to Mary Hardin-Baylor 24-17 in second round of Division III playoffsDespite a 17-point second half, Trinity could not overcome a 10-point halftime deficit in a 24-17 loss to the defending Division III National Champions Mary Hardin-Baylor on Saturday.
続きを読む »
Laval celebrates as Huskies come up short in second consecutive Vanier CupThe U of S Huskies lost 30\u002D24 to Laval in Saturday\u0027s Vanier Cup — their second national\u002Dtitle loss in as many years.
続きを読む »