Golden staph are ubiquitous bacteria, living harmlessly on the skin or inside the nose of nearly one in three people worldwide.
strains taken from patients with bloodstream infections using InToxSa, and observed specific changes that make the bacteria less harmful and better at surviving in our bodies," Hachani"We identified the genes that control the bacteria's ability to persist inside host cells without killing them," heGolden staph is often considered an extracellular pathogen, the researchers write, which is a free-living microbe capable of causing disease without invading the cells of its host.
But it's not exclusively extracellular, they add, noting that golden staph can also survive and replicate inside its host's cells. This tactic may kill the host cells, but it helps the bacteria avoid detection by the host's immune system. Using InToxSa, Hachani and his colleagues studied 387 golden staph strains from patients who had the species living in their blood. They identified specific mutations that make
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