By tracing every single connection between nerve cells in a single fruit fly’s brain, scientists have created the “connectome,” a tool that could help reveal how brains work.
In the brain of a singular fruit fly, nerve cells weave themselves together, enabling flight, mating, eating, sleeping and every other activity of her fly life. Now, in nine papers published October 2 inThis whole-brain map, traced over years with painstaking precision, is tiny but exquisite: It holds 149.2 meters of neural wiring, all tidily packed into a brain about the size of a poppy seed.
“Did we think it was going to take this long, like, almost 20 years later we would have the fly connectome? Probably not,” says Sebastian Seung, a computational neuroscientist at Princeton University. “But overly optimistic people drive progress.” In this fruit fly brain, there are precisely two neurons called CT1 neurons that span the width of the eye. Each of these neurons makes over 140,000 synapses and uses its unique position to help the fly sense light and motion.
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