'The technique is both safe and effective in mice.'
But that doesn't mean we'll be able to turn back the clock in humans any time soon, as we still don't fully understand the implications the therapy has on health. And, needless to say, mice are very different from people.
In an experiment to test if the approach was safe, Izpisua Belmonte — that's the Salk scientist behind this latest study — and colleagues tested a range of rejuvenation approaches on three groups of lab mice of different ages, giving them doses of Yamanaka factors at regular intervals. Compared to a control group of mice that didn't receive treatment, the mice resembled their younger selves, showing an improved ability to regenerate skin cells and reduced scarring.The effect was most pronounced in groups in which the mice received the treatment for seven to ten months, the equivalent of around 15 human years.
We're also far from being able to tell if the same technique could be used in humans to reverse aging — or if it's safe to do so in the first place.
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