SARS-CoV-2 Omicron BA.4.6 resistant to many therapeutic monoclonal antibodies in clinical use Antibodies Omicron SARSCoV2 Coronavirus Disease COVID biorxivpreprint ColumbiaPS q_nationaltaiwa
Study: Resistance of SARS-CoV-2 Omicron Subvariant BA.4.6 to Antibody Neutralization. Image Credit: Naeblys / Shutterstock
About the study The present study compared the spike protein binding affinity of the Omicron sub-variants BA.4.6, BA.4.7, and BA.5.9 against that of the globally dominant BA.5 sub-variant. The assays included the spike proteins from the lineages carrying R346T, R346S, and N658S point mutations and the spike proteins of the BA.4 and B.4 sub-lineages.
Results Related StoriesThe study results showed that Omicron sub-variants BA.4.6, BA.4.7, and BA.5.9 exhibited similar binding affinities to the dimeric human angiotensin-converting enzyme 2 receptor compared to the BA.5 subvariant. The pseudoviruses carrying point mutations also displayed binding affinities similar to BA.4.6.
Additionally, the therapeutic monoclonal antibody combination of cilgavimab and tixagevimab was found to be ineffective against all three newly emergent mutated sub-variants.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Newcastle United match now called off - I've heard that somewhere before...Newcastle United match now called off - I've heard that somewhere before... nufc
続きを読む »
Michael Owen in new shameful disrespectful behaviour towards Newcastle UnitedHe is at it again, Michael Owen in new shameful disrespectful behaviour towards Newcastle United.
続きを読む »
Leeds United youngster makes exciting claim upon securing international callA Leeds United youngster has made an exciting claim upon securing an international call.
続きを読む »
Mike Ashley austerity Newcastle United elevenIntroducing the Mike Ashley austerity Newcastle United eleven.
続きを読む »
Beatrice and Eugenie among Royals united in grief for Balmoral church servicePrince Andrew, Princess Anne and the Wessexes were also among the members of the Royal family who attended a service at Crathie Kirk, Balmoral on Saturday afternoon
続きを読む »