Resistant starch is a nondigestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive effect on metabolism in animal studies. Now, a 4-month randomized controlled trial in people with non-alcoholic fatty liver disease (NAFLD) indicates that daily intake of resistant starch can alter gut bacteria composition and lower liver triglycerides and liver enzymes associated with liver injury and inflammation.
NAFLD, caused by a buildup of fat in the liver, affects about 30% of the population worldwide. It can lead to severe liver diseases and contribute to other conditions, such as type 2 diabetes and cardiovascular disease. Currently, there is no approved medicine available to treat NAFLD. Doctors usually recommend dietary changes and exercise to alleviate the conditions.
Previous research has suggested that NAFLD is associated with perturbed gut microbiota. For example, people with early-stage NAFLD already have an altered gut bacteria profile. So, Li and her team wanted to investigate if resistant starch -- a type of fiber known to encourage the growth of beneficial gut bacteria -- can help treat NAFLD.
After the 4-month experiment, participants who received the resistant starch treatment had nearly 40% lower liver triglyceride levels compared to patients in the control group. In addition, patients who had the resistant starch treatment also saw reductions in liver enzymes and inflammatory factors associated with NAFLD. Importantly, these benefits were still apparent even when statistically adjusted for weight loss.
By analyzing patients' fecal samples, the team found the resistant starch group had a different microbiota composition and functionality compared with the control. In particular, the treatment-group patients had a lower level ofa key bacterial species that can affect fat metabolism in the liver through its metabolites. The reduction inis stronglylinked to the decrease in liver triglyceride content, liver enzymes, and metabolites observed.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Characterization of methicillin-resistant Staphylococcus aureus from ready-to-eat foods in ChinaThe objective of a new study published in the journal Zoonoses was to determine the prevalence, antimicrobial resistance, virulence profiles, and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) obtained from ready-to-eat (RTE) foods in China.
続きを読む »
Best Buy's deal of the day is $40 off a Google Nest CamThe Google Nest Cam, a weather-resistant security camera that can go battery-powered or wired, is currently on sale for just $140 from Best Buy for Labor Day.
続きを読む »
New genes and natural toxins offer hope for cancer patients unresponsive to chemotherapyScientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it.
続きを読む »
Smash Mouth's Steve Harwell Is in Hospice Care Amid Liver FailureFormer Smash Mouth frontman Steve Harwell is receiving end-of-life care at home amid liver failure
続きを読む »
Smash Mouth singer Steve Harwell 'on deathbed' and suffering from liver failureFormer Smash Mouth lead singer Steve Harwell has entered hospice care during his ongoing battle from liver failure, which was reportedly brought on by alcoholism.
続きを読む »
Smash Mouth singer Steve Harwell in hospice for liver failureSmash Mouth singer Steve Harwell in hospice for liver failure with 'only a week or so to live', EW can confirm.
続きを読む »