Researchers are working on new ways to detect Alzheimer’s before you or anyone else knows you have it.
More than six million Americans are living with Alzheimer’s today. Half a million more people will be diagnosed this year. But thousands of cases of Alzheimer’s disease go undiagnosed each year. That’s because the changes in the brain can begin at least 10 years or more before symptoms start. Now, researchers are working on new ways to detect this disease before you or anyone else knows you have it.
Retirement was a never-ending adventure for John and Lynn Struckhoff, as they traveled the country in their fifth wheel. The two have been on a journey together for five decades.They were on the road when John started seeing his wife slowly change. After several cognitive tests, doctors believed it was Alzheimer’s.
John recalls, “I said, ‘Well, how do we know for sure?’ They said, ‘Well, the only way we really know is an autopsy and that's not a practical thing right now.’” John enrolled Lynn in a clinical trial that tests a person’s blood for changes in the brain. The test measures the amount of amyloid beta proteins called A-beta 42 and A-beta 40 in the blood. The less A-beta 42 in the blood, the more likely you are to have Alzheimer’s.
“The A-beta 42 is getting stuck in the plaque, so it's not ending up in the spinal fluid or in the blood,” explains Washington University School of Medicine neurologist, Suzanne Schindler, MD, PhD.
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