Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi MlwTrust LivUni UofGlasgow LSHTM SARSCoV2 infection covid coronavirus covid Omicron
By Tarun Sai LomteJan 23 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in eClinicalMedicine, researchers conducted a serosurvey during the severe acute respiratory syndrome coronavirus 2 Omicron wave in Malawi.
About the study In the present study, researchers estimated the seroprevalence of SARS-CoV-2 in seven districts across Malawi. Individuals aged five or older were eligible for inclusion from December 27, 2021, to January 17, 2022. A standard COVID-19 screening tool was leveraged to obtain information on demographics, socioeconomic status, COVID-19 vaccination status, and chronic illnesses.
Seropositivity was estimated, and seroprevalence was adjusted for the sensitivity and specificity of each assay. Fisher’s exact or chi-squared test was used to estimate the proportion of subjects by the number of vaccine doses received. Multivariable logistic regression was performed to identify factors associated with SARS-CoV-2 seropositivity.
Around 12% of participants were partially vaccinated, and 11% received two vaccine doses. Vaccination coverage and the proportion of two-dose recipients were higher among participants aged 51 or older than those aged 18 – 50. Urban areas had more double-vaccinated individuals than rural areas.
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