Research and treatment of psychiatric disorders are stymied by a lack of biomarkers - objective biological or physiological markers that can help diagnose, track, predict, and treat diseases.
Nov 9 2023Elsevier In a new study, researchers use a very large dataset to identify predictive brain imaging-based biomarkers of mental illness in adolescents. The work appears in Biological Psychiatry, published by Elsevier.
In the current study, the investigators used brain imaging data from the Adolescent Brain Cognitive Development Study of nearly 12,000 children aged 9 to 10 at the beginning of the study. Modern neuroimaging techniques, including resting-state functional connectivity analysis, allow researchers to investigate the organization of brain circuits through their interaction with one another over time.
Cognition has long been studied in the context of mental disorders, and recent research has pointed to shared neurobiology between the two, as supported in this new study. Related StoriesDr. Yang added, "These findings provide evidence for a transdiagnostic brain-based measure that underlies individual differences in developing psychiatric disorders in early adolescence."
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