Could this be the youth potion we have been waiting for? 🤔 engineering
“We are elated that we can use this approach across the life span to slow down aging in normal animals. The technique is both safe and effective in mice,” said in the statement co-corresponding author Juan Carlos Izpisua Belmonte“In addition to tackling age-related diseases, this approach may provide the biomedical community with a new tool to restore tissue and organismal health by improving cell function and resilience in different disease situations, such as neurodegenerative diseases.
The researchers tested the cocktail of molecules in three different test groups one of which consisted of mice followed through from the time they were 12 months through to 22 months, approximately age 35 to 70 in humans. They found that even in such a long timespan the molecules were safe for the animals and produced impressive anti-aging results.The other two test groups were given the cocktail from 15 months old until 22 months, approximately equivalent to age 50 through 70 in humans, and for just one month one at age 25 months, similar to age 80 in humans.
There is one catch, however, the treatment needs to be implemented for a period longer than seven months in order to be effective. Mice treated for only one month showed no signs of youthfulness. The team is now working on identifying how specific molecules and genes are changed by long-term treatment with the molecules.“At the end of the day, we want to bring resilience and function back to older cells so that they are more resistant to stress, injury, and disease,” added Reddy. “This study shows that, at least in mice, there’s a path forward to achieving that.”