Research evaluates neonatal outcomes of pregnancies complicated by maternal obesity Neonatology Obesity Pregnancy neonatal morbidity BMI mortality AJOG_thegray ajogmfm
By Dr. Liji Thomas, MDJan 25 2023Reviewed by Benedette Cuffari, M.Sc. Obesity is linked to many adverse health outcomes, including in pregnancy. However, there is little information on the effect of maternal obesity on neonatal mortality and illness.
Introduction Maternal obesity is relatively common in pregnancy, with about one-third of pregnancies in the United States complicated by obesity. Obesity is linked to maternal hypertension, diabetes, and pre-eclampsia, as it is a chronic inflammatory state. Maternal BMI was classified into the reference group of normal/overweight. The experimental groups of obese , morbidly obese , and super-morbidly obese were categorized based on BMI, with values ranging from 30-39.9 kg/m2, 40-49.9 kg/m2, and 50 kg/m2 or more, respectively. Reference BMI values were between 18.5-29.9 kg/m2.
What did the study show? Related StoriesThe current study included over 52,000 patients and their neonates, 42% of whom were OB, and 7% and 1% were MO and SMO, respectively. Obesity was associated with pre-existing diabetes, chronic hypertension, and cigarette use, increasing with BMI, though at a lower rate compared to the reference group.
The risk of neonatal morbidity increased by one-third in neonates born to MO mothers compared to those born to women in the reference group. However, no such association was observed for babies born to OB or SMO mothers. Pre-existing obesity and obesity in early pregnancy might predict an increased risk of more significant neonatal morbidity.
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