People with hospital-treated infections in early- and mid-life had the greatest risk of Alzheimer’s and Parkinson’s diseases later in life. Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s (AD) and Parkinson’s d
and Parkinson’s diseases later in life.
Experimental studies in animals have indicated that infection plays a role in the development of some neurodegenerative diseases. However, supporting evidence in humans is limited. In the new study, scientists used data on people diagnosed with AD, PD, or ALS from 1970-2016 in Sweden, as well as five matched controls per case, all identified from the Swedish National Patient Register. The analysis included 291,941 AD cases, 103,919 PD cases, and 10,161 ALS cases.
Researchers assess hospital-treated infection and risk of neurodegenerative diseases. Credit: Jiangwei Sun
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