The therapeutic potential of resveratrol, a red grape polyphenol.
By Pooja Toshniwal PahariaOct 25 2023Reviewed by Lily Ramsey, LLM In a recent review published in Nutrients, researchers reviewed existing data on the therapeutic potential of resveratrol, a red grape polyphenol.
About the review In the present review, researchers described the sources, metabolism, health benefits, properties, and mechanism of action of resveratrol. The drug also aids in treating depression, preventing brain damage, and improving cognition. Further, resveratrol can help with intestinal swelling, digestion, and constipation. In adipose tissues, it can affect fat cell development and mitochondrial synthesis.
Resveratrol has anti-diabetic effects via lowering glucose bioavailability and boosting the levels of 5′-AMP-activated protein kinase , sirtuin type 1 , and peroxisome proliferator-activated receptor-coactivator one alpha . Resveratrol inhibits cancer growth by preventing cell proliferation and deoxyribonucleic acid damage, increasing nuclear factor-kB , wingless-related integration site , tumor necrosis factor-alpha , RAS association domain family isoform A , and B-cell lymphoma 2 levels, and decreasing Bcl-2-associated X protein and caspase-3 levels.
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