Protein p53 regulates learning, memory, sociability in mice

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Protein p53 regulates learning, memory, sociability in mice
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Researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and conditions like autism spectrum disorder.

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The mutation of a gene that has been associated with neurodevelopmental disorders like autism spectrum disorder led to marked sleep disturbances in fruit flies, according to a new study. The findings ... A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice. These mice then showed severe alterations of specific behaviors that closely ...

A study has uncovered a brain-signaling pathway that can be pharmacologically manipulated in mice to reverse an autism-related pathway. Using an experimental drug targeting this pathway, researchers ...

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New Research Uncovers That a Certain Protein Is Directly Linked to Autism-Like BehaviorNew Research Uncovers That a Certain Protein Is Directly Linked to Autism-Like BehaviorNew findings shed light on the link between the TP53 protein-coding gene and neurodevelopmental and psychiatric conditions such as autism spectrum disorder. Researchers have established that the protein p53 plays a crucial role in managing sociability, repetitive behavior, and learning and memory
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