Powerful New Drug Prevents STIs, But May Come With a Hidden Catch

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Powerful New Drug Prevents STIs, But May Come With a Hidden Catch
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The United States is set to roll out a powerful new weapon in the long fight against sexually transmitted infections: a decades-old antibiotic repurposed as a preventative pill.

DoxyPEP, or doxycycline used as a post-exposure prophylaxis, has been found to significantly cut the risk of chlamydia, gonorrhea and syphilis when used after condomless sex.

Several issues are behind the rise: fewer people are using condoms since the advent of PrEP – daily pills that significantly reduce chances of contractingAnd people who are on PrEP are recommended to undergo screening every three months, likely increasing the identification of infections. Though they found the rate of resistant gonorrhea slightly higher in the DoxyPEP group, she says the finding could simply mean the pill is less effective against already resistant strains, rather than causing that resistance.

But Stephen Abbott – a doctor at Washington's Whitman-Walker clinic who prescribes and uses DoxyPEP – said it's crucial to meet people where they are.

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