Potentially 'Novel' COVID-19 Therapy Reported by Cedars-Sinai Scientists Stops Virus Replication, Protects Infected Cells

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Potentially 'Novel' COVID-19 Therapy Reported by Cedars-Sinai Scientists Stops Virus Replication, Protects Infected Cells
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Scientists report a biologic substance created with skin cells called dermal fibroblasts stopped SARS-CoV-2 from reproducing and protected cells when tested in human lung cells.

Scientists from Cedars-Sinai report research findings have opened the possibility to a new therapy for COVID-19 patients, a discovery made in a biologic substance created by reengineered human skin cells.

The substance stopped SARS-CoV-2, the virus that causes COVID-19, from reproducing and protected cells when tested in human lung cells, scientists reported. The research is in early stages."We were surprised to find this potential therapy shuts down a novel pathway for viral replication and also protects infected cells,'' Ahmed G. Ibrahim, PhD, MPH, assistant professor in the Smidt Heart Institute at Cedars-Sinai and first author of the study, said in a statement.

The new findings for potential treatment inhibits replication, but also protects or repairs tissue, an important step because COVID-19 can cause symptoms that affects patients long after being infected by the virus. Scientists say there are few treatments that exist for COVID-19, and the ones that do exist focus on preventing the virus from replicating.Investigators at UCLA collaborated in the study and research.

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