The bacterium that causes the infectious disease could potentially regrow liver cells.
Researchers have discovered that leprosy bacteria can reprogram cells to increase the size of the liver in adult animals. This can be done without damaging or scarring the organ. It also did not create tumors when the liver grew in size.Leprosy, one of the oldest and most persistent infectious diseases, may have the ability to regenerate livers, according to a new study.
In order to counteract the harmful side effects, researchers expanded on their previous breakthrough for liver regrowth by looking into their study involving Mycobacterium leprae , the bacteria that causes leprosy.The researchers studied the effects in armadillos, natural hosts to the bacteria The research team, who worked with the U.S. Department of Health and Human Services in Baton Rouge, Louisiana, U.S., infected 57 nine-banded armadillos with the bacteria ML. The team chose the animals specifically because they are natural hosts of the leprosy bacteria. Then, they compared the infected armadillos’ livers with those that were uninfected and others that were resistant to infection.
They noticed that the infected animals developed enlarged, healthy livers with the same vital components, such as blood vessels, bile ducts and functional units called lobules, as the uninfected and resistant animals. The team thinks the bacteria ‘hijacked’ the regenerative ability of the liver to increase the organ’s size, providing it with more cells to grow bigger, giving the organ the ability to increase and renew itself.
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