A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.
Mar 9 2024Nagoya University A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis . The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.
Until now, researchers have reported six genes associated with GPP. Although these genes are widely used for diagnosis and treatment, there remain GPP patients who do not have any variants of these genes. This suggests unknown genetic factors associated with the development of GPP. Pyrin, the product of MEFV, regulates inflammatory pathways. But specific variants of pyrin induce excessive neutrophil migration to tissues, eventually triggering excessive inflammation. This finding, therefore, suggests a likely path for the disease.
日本 最新ニュース, 日本 見出し
Similar News:他のニュース ソースから収集した、これに似たニュース記事を読むこともできます。
Japan Day celebrated at Preston’s university for 10th yearEvent organiser Chisa takes to the catwalk wearing the traditional Japanese kimono. Pic: UCLan The University of Central Lancashire (UCLan) hosted its annua
続きを読む »
Pity: An Evocative New Novel About Queer Life in the North of EnglandAn empathetic portrait of a misunderstood community, Andrew McMillan’s debut novel Pity tells the story of a shopping centre security guard and a call centre employee with two very contemporary side hustles: drag and OnlyFans
続きを読む »
Culture Chat: Margaret Atwood, John Grisham and friends write a novelIn an experiment whose proceeds will go to the Authors Guild of America, 36 authors including Margaret Atwood, John Grisham, Dave Eggers, and Celeste Ng, wrote a collaborative novel
続きを読む »
Exploring the effectiveness of a novel pain management device for endometriosis painEndometriosis is a chronic condition affecting women, often resulting in painful symptoms such as menstrual cramps and pelvic pain. Pain caused by endometriosis significantly lowers the quality of life and reproductive health of affected women, with around one-third of women still experiencing pain and discomfort despite treatment.
続きを読む »
Novel technique could transform the treatment landscape for brain disordersThe human brain's adaptability to internal and external changes, known as neural plasticity, forms the foundation for understanding cognitive functions like memory and learning, as well as various neurological disorders.
続きを読む »
Novel therapy harnesses stem cell-derived exosomes for diabetic wound healingResearchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.
続きを読む »