The breakthrough light-activated cancer therapy has drug molecules permanently fixed to a tumor.
The next generation of light-activated cancer treatments sounds years away, but in what can be called a breakthrough, scientists at the University of East Anglia got several steps closer.embedded near a tumor are switched on, it activates biotherapeutic drugs. These are highly targeted and would be more effective and precise than current immunotherapies.
Now, antibodies and antibody fragments have already been developed to treat cancer. The UEA team has engineered "one of the first antibody fragments that bind to and forms a covalent bond with its target - upon irradiation with UV light of a specific wavelength," as per the release.
Sachdeva stressed that the treatment would work for cancers like that of the skin or where there is a solid tumor but not for blood cancers like leukemia.If the next stage of research goes well, the 'next generation' light-activated immunotherapies could treat cancer patients within five to ten years.Design of biomolecules that perform two or more distinct functions in response to light remains challenging.
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