'These kidneys are going to last forever,' one researcher said.
, or SIOD, that often destroys a person's ability to fight off infection and leads to kidney failure. In each case, a parent donated stem cells taken from bone marrow, as well as a kidney.
Coaxing the body away from rejecting a transplanted organ has always been an uphill battle, Tevar said."The Holy Grail of transplantation is immune tolerance," meaning that the body doesn't view a donated organ as a threat worthy of attack.An advance in kidney transplantation could have far-reaching impact. Nearly 90,000 people in the U.S. are waiting for a new kidney, according to theDr.
Recipients are generally required to stay on drugs to suppress their immune system for as long as they have the donated organ. Those medications raise the risk for serious problems, such as high blood pressure, cancer and infections severe enough to require hospitalization. Kruz, who turns 9 next month, and his 7-year-old sister, Paizlee, are only the second set of siblings in the world documented with SIOD, Jessica Davenport said. The condition is a type of dwarfism that impacts multiple systems in the body. It's generally marked by an inability to grow typically, kidney failure and a deficiency in T-cells, which help the body fight off infections.Family photo
A third child in the report has not been identified. Bertraina said the child, a girl, had been dependent on dialysis previously, which affected her quality of life.Reducing need for immunosuppression drugs There are limitations to the procedure. Though the kids' kidneys and immune systems are working well for now, these ansplants are not a cure for SIOD. Both Kruz and Paizlee continue to have complications, including debilitating migraines and risks for stroke and other cardiovascular problems."There are many other types of kidney diseases where the body is still producing factors to damage tht kidney," Rabb said.
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