New analysis of Indonesia Wolbachia trial shows potential for greater dengue reduction

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New analysis of Indonesia Wolbachia trial shows potential for greater dengue reduction
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The fight against dengue fever has a new weapon: a mosquito infected with the bacteria Wolbachia, which prevents the spread of the virus.

Reviewed by Danielle Ellis, B.Sc.Nov 6 2023 These mosquitoes have now been deployed in several trials demonstrating their potential in preventing disease transmission.

Alex Perkins, associate professor of biological sciences at Notre Dame and senior author on the study The study found that the amount of bias introduced in any given trial is likely to be greater when the population receiving the intervention in the trial is larger. In the case of the Indonesia trial, nearly half the population was treated with Wolbachia mosquitoes. "That makes the bias that we uncovered due to transmission coupling especially important for this trial," Perkins said.

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