A Review published in Cell & Bioscience provides an updated picture of the different pharmacological approaches to treat cancer, focusing on the use of nanoparticles for autophagy modulation.
in vivo models to the clinic may be due to the fact that established cell lines conventionally used to validate nanoformulations may do not reflect the heterogeneity existing among human individuals.
Advanced nanoparticles have been revealed as potential smart drug delivery systems to improve the therapeutic effect of current standard drugs and increase patient survival rates. Undoubtedly, there is still a long journey from the nanocarriers design to translation to the pharmaceutical market as viable products.
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