After the patients were administered the drugs in the New York facility, an electrocardiogram revealed cardiac rhythm problems in many people treated.
The anti-malarial drugand azithromycin, an antibiotic used to treat many infections caused by bacteria, have been widely touted as a treatment to reduce the symptoms of patients diagnosed with COVID-19.
When the QTc interval is prolonged, a patient can be at risk of arrhythmia—a disorder of the heart that affects the rate or rhythm at which the heart beats—and sudden cardiac death. The QTc was severely prolonged in 11 percent of the patients, which put them at high risk of arrhythmia and sudden cardiac death. Four patients in the group died from multiple organ failure, without evidence of arrhythmia and without severe QTc prolongation.who were treated with hydroxychloroquine and azithromycin experienced QTc prolongation.
The authors concluded that the QTc in patients with COVID-19 who are treated with hydroxychloroquine and azithromycin should be monitored constantly.
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