Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

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Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination
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Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination ITMantwerp monkeypox virus virology disease vaccination epidemiology

By Suchandrima BhowmikSep 12 2022Reviewed by Danielle Ellis, B.Sc. The first detection and transmission of the monkeypox virus outside its endemic areas in May 2022 was followed by a huge multi-country outbreak worldwide. As of the 23rd of August 2022, a total of 42,807 cases along with 12 deaths were reported across 97 member states that belong to six World Health Organization Regions.

About the study The study was carried out using data submitted to the European Surveillance System . Nowcasting of the TESSy data was carried out up to 17 days before the last reported symptom to understand the current epidemiological situation. Out of the total 21,098 cases detected in the WHO European Region, 20,690 cases provided case-based data, most of which were laboratory confirmed. Nowcasting results suggested an overall plateauing of cases with a few inter-country differences. Additionally, most cases were males with a median age of 37 years. Among them, 96.9% self-identified themselves as MSM, while 37.2% were found to be HIV positive. Very few cases were reported among children and women.

Furthermore, the case hospitalization ratio was reported to be 10 per 1,000 cases, with younger cases having a higher risk of hospitalization. Regarding transmission routes, sexual contact was the most possible route followed by person-to-person routes or fomites. Exposure at bars and household exposures were also reported to play a role in transmission. Additionally, 64 of the cases were observed in health workers, of whom 62 were male, and 55 were MSM.

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