An expert panel recommended a risk-stratified approach to melanoma screening, but the jury is still out for gene expression profile testing. OncTwitter
Detecting melanoma early, when it is easier to treat, remains a"paramount goal," but guidelines surrounding optimal melanoma screening practices and diagnostic evaluations need greater clarity, according to the authors of aThat is why a group of expert panelists evaluated the existing evidence and a range of clinical scenarios to help clarify the optimal strategies for early detection and assessment of cutaneous melanoma.
In the prebiopsy setting, the appropriate use of diagnostic tools for evaluating the need for biopsy remain poorly defined and, in the post-biopsy setting, questions remain concerning the diagnostic accuracy of molecular techniques, diagnostic GEP testing, next-generation sequencing, and immunohistochemical assessment for various markers of melanoma.
Panelists agreed that those at general or lower risk could be screened by a primary care provider or through regular self- or partner examinations whereas those at moderate risk could be screened by their primary care clinician or general dermatologist. The experts observed"a shift in acceptance" of primary care physicians screening the general population, and an acknowledgement of the importance of self- and partner examinations as screening adjuncts for all populations.
"The panelists await future, well-designed prospective studies to determine if use of these and newer technologies improves the care of patients with melanoma," the panelists write.
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