In recent years, microfluidics has emerged as a revolutionary technology for biological analysis and medical diagnostics, enabling the precise control and manipulation of fluids at the microscale. At the same time, functionalized magnetic beads have become an indispensable tool for the selective capture and enrichment of target analytes.
Facing the development of current magnetic control technology, Professors Jianlong Zhao and Shilun Feng's team from Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences has made a detailed categorization and introduction on the mechanisms of magnetic bead manipulation in microfluidic chips.
These methods have different application advantages according to the movement states and detection purposes of magnetic beads.
"Although the magnetic manipulation system has been greatly developed, it still has many remaining challenges when facing industrial and clinical applications," said Feng, pointing out that the current sample processing throughput of magneto-microfluidic chips is still low, which cannot meet the needs of large-scale clinical testing.
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