Long-Lasting Brain Changes: Irreversible Neuronal Disruptions From Binge Drinking in Adolescence — A study conducted at Penn |
A Penn State study suggests that adolescent binge drinking could cause irreversible changes in the brain’s neural signaling. Using a mouse model simulating binge drinking during developmental years, researchers found that key neurons exhibited overexcitability long after alcohol consumption had ceased, hinting at the potential for lasting cognitive and behavioral changes.
“What we’re seeing here,” said Nikki Crowley, assistant professor in biology and biomedical engineering and Huck Early Chair in Neurobiology and Neural Engineering, “is that if adolescent binge drinking knocks neurons off this trajectory, they might not be able to get back, even if the alcohol consumption stops.”
Penn State neuroscience doctoral student Avery Sicher works in the lab, doing patch-clamp electrophysiology. Credit: Dan Lesher / Penn State
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