'Koala AIDS' research reveals genome evolution in action

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'Koala AIDS' research reveals genome evolution in action
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Wild koalas sickened by a deadly retrovirus are fighting the disease at the genetic level, scientists said Thursday, a rare evolutionary process unfolding before our eyes. It is linked to Koala Immune Deficiency Syndrome (KIDS), which is similar to but less potent than AIDS in humans, and makes the

1 / 2The KoRV-A retrovirus first began infecting koalas between hundreds to a few thousand years ago, starting from the north of Australia and spreading south, and may have come from batsThe KoRV-A retrovirus first began infecting koalas between hundreds to a few thousand years ago, starting from the north of Australia and spreading south, and may have come from bats Washington - Wild koalas sickened by a deadly retrovirus are fighting the disease at the genetic level, scientists said Thursday,...

It's feared that if left unchecked, these various misfortunes could eventually lead to the iconic animal's demise. Sometimes the viruses are co-opted for useful purposes, including one responsible for the evolution of the placenta in our mammalian ancestors around 100 million years ago. Their findings suggest that germ cells recognize an essential step in the viral life cycle and turn it against the invader to suppress genome infection by being able to tell the difference between its own cells and the virus.

"So we're seeing the initial response," said Theurkauf."The question is, can we find koalas that have turned on the next phase where they're really shutting it down?"

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