New research from Karolinska Institutet in Sweden shows how oestrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic.
Mar 9 2024Karolinska Institutet The study, published in Molecular Systems Biology, shows how a new drug under development could become a future treatment for fatty liver disease and liver cancer.
Women protected until menopause However, the disease is very unevenly distributed between the sexes, with a large majority of affected individuals being men. Through genetic analyses of mice of both sexes fed a high-fat diet, with some of the male mice also receiving oestrogen, the researchers were able to identify a key protein in the development of fatty liver.
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Study shows how estrogen protects against fatty liverNew research from Karolinska Institutet shows how estrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic. The study, published in Molecular Systems Biology, shows how a new drug under development could become a future treatment for fatty liver disease and liver cancer.
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