GRIM DIAGNOSIS: Baby formula is just the tip of the supply chain shortage iceberg, Dr. Siegel says.
Sen. Marsha Blackburn, R-Tenn., responds to Commerce Secretary Gino Raimondo's claims that the Biden administration learned of America's formula crisis in April.Lest you think the baby formula shortage occurred overnight or is an isolated problem, think again. It can and will be solved with fewer regulations, a worldwide market, a Trumpian style public/private partnership, and a deep reserve. But baby formula is just the tip of the supply chain shortage iceberg.
As with baby formula, the problem starts with big pharma territoriality, where the definition of chemicals is narrow, and the level of competition is insufficient. Dr. Scott Gottlieb, when he was FDA commissioner, took a big step in adding biosimilars and generic versions of older drugs to the insulin market but these efforts have thus far proven insufficient to keep prices down or ensure sufficient product.
According to the Centers for Disease Control and Prevention there are 37.3 million people with diabetes in the U.S. which is 11 percent of the U.S. population. An additional 96 million over the age of 18 have prediabetes. 7.4 million Americans with diabetes use one or more formulations of insulin and this number is growing. Unfortunately, the insulin supply is not. Just the opposite, in fact.
The FDA announced just before the pandemic started, in February, 2020, that there was going to be a drug shortage including insulin due to the initial COVID outbreak in China.600 percent in the past 20 years, and at least three states, California, Washington, and Maine, have been passing legislation with the intention of producing their own insulin, as has Civica RX, a consortium of health care providers, insurers and philanthropists.
The solution is multi-faceted and it includes more generics, biosimilars, public production, federal reserve, management algorithms and slow replacement of insulin with newer drugs which boths and also decrease hunger and weight, a handy"two-for" which decreases insulin requirements. The new Lilly drug, tirzepatide, is very promising in this regard. But of course, there will be shortage of these drugs too and many insurances are not routinely covering them.
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